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Translational Endocrinology of Bone. Gerard Karsenty. Benjamin Bonavida. Pharmacogenomics of Human Drug Transporters. Toshihisa Ishikawa. Atta-ur- Rahman. Swapan K.

Recent Advances in Peroxisome Proliferator-Activated Receptor Science

Targeted Therapy in Translational Cancer Research. Apostolia-Maria Tsimberidou. William G. Advances in Biology and Therapy of Multiple Myeloma. Nikhil C. Targeting the Wnt Pathway in Cancer. Kathleen H. Tumor Microenvironment and Cellular Stress. Constantinos Koumenis. Daniel E.

Glycosignals in Cancer: Mechanisms of Malignant Phenotypes. Koichi Furukawa.

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Sadegh Babashah. Cellular Injury in Liver Diseases. Wen-Xing Ding. Current Challenges in Personalized Cancer Medicine. Keiran Smalley. Nitric Oxide NO and Cancer. Thomas Decker. Brian Henderson.

Peroxisome proliferator-activated receptors : discovery and recent advances in SearchWorks catalog

Cancer Immunology and Immunotherapy. Glenn Dranoff. Tumor-Induced Immune Suppression. Dmitry I. Nikki P. Translational Research in Breast Cancer. Erwei Song. Stem Cells and Prostate Cancer. Scott D. Jiri Neuzil. Signal Transduction in Cancer Metastasis.

Wen-Sheng Wu. Prostate Cancer: Shifting from Morphology to Biology. Stefania Staibano. Molecular Pathogenesis of Colorectal Cancer. Kevin M. Negative Co-Receptors and Ligands. Rafi Ahmed. Epigenetic Therapy of Cancer.

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Xiaojing Ma. The IGF System. Synthetic PPAR agonists have exhibited therapeutic benefits in treating diabetes and cardiovascular diseases. The discovery of PPAR-specific ligands has led to significant advancement in our understanding of the structure of these receptor proteins and the molecular mechanism of their ligand-dependent activation. Herein, we present both recent progress in the functional analysis of these orphan receptors and the confirmation of the PPARs as molecular targets for the development of new medicines to treat human metabolic disease.

Peroxisome Proliferator-Activated Receptors (PPARs)

Keywords: peroxisome proliferator, ppar, nuclear receptor, ppar agonists, ppar-specific. Abstract: The peroxisome proliferator-activated receptor PPAR family of nuclear receptors, a set of three receptor sub-types encoded by distinct genes, function as lipid sensors to regulate a broad range of genes in many metabolically active tissues. Barry G. Shearer and William J. Shahidul Islam. Ovarian Cancer. Sharon Stack. Heat Shock Protein Inhibitors.

ISBN 10: 1627034196

Shelli R. Targeted Cancer Immune Therapy. Joseph Lustgarten. Catherine M.